Sampling Science & Technology (SST) is a free publication for the sampling community, providing a communications platform for all interested in the theory and practice of representative sampling and blending. SST aims both to serve the world sampling community and to disseminate awarenes of proper sampling practices to all other interested parties in science, technology, industry, commerce, as well as to supervising and regulating authorities.

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PAT: Something Completely Different

The scope for this issue is ‘Sampling for PAT’. For a very large proportion of traditional samplers and a great many readers of SST the term PAT is undoubtedly rather unknown. For this reason, SST has commissioned two educational lead-in feature articles 1) “What is PAT?” and 2) “The inspiring role of TOS in the PAT revolution in pharma”. These articles present authoritative introductions and descriptions of applied Process Analytical Technology (PAT) with scopes that aim and prepare for generalisation: While having had a tremendous impact in the pharmaceutical industrial sector for three-four decades, PAT has simultaneously transgressed way outside its own borders. Perhaps without having made a great splash in the world sampling community, there actually have appeared several recent forays making use of selected aspects of PAT (WCSB10, 11), but these have lacked a structured theoretical underpinning. This is addressed heads on by the third article, “The Fundamental Sampling Principle for PAT”.

For quite some years it has been a wish of the editor to present to the sampling community a more diverse introduction to PAT: scope, concept, design, implementation, usages and application experiences, which was finally realised with a broad solicitation. Six very experienced experts responded positively. Thus, in this issue some very inspiring accounts of the current interface between TOS and PAT can be found. All hail to HK, HM, DK, BS, RR and GR. I hope you will enjoy reading this multi-faceted collection of reflections and experiences from this distinguished line-up of practitioners, scientists and technology developers, academic and commercial both. It is hoped the present compendium will create a platform and will inspire to further PAT developments in the sampling realm. There are undoubtedly great potential benefits to be reaped as the possibilities for Process Analytical Technologies are put into practice – but it is also necessary to express serious warnings. Successful PAT applications are far from the all-too-simplistic idea of sticking a sensor into the process stream. The sampling community can learn a very great deal from this issue!

Then there is the domain of analysis sensu stricto. For want of space it has been decided not to go into this immense domain in this issue [...]

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About the International Pierre Gy Sampling Association

Sampling Science and Technology (SST) is published by the International Pierre Gy Sampling Association (IPGSA). The purpose of IPGSA is to oversee formal activities of the world sampling community and to represent the views of this community.

The Association is a common-interest, unincorporated association of individuals solely associated for the common purpose of promoting the interests of the international sampling community and its various activities.

About the Editor

Kim H. Esbensen

Sampling Science & Technology (SST) is edited by Professor Kim H. Esbensen. Esbensen is an international expert and consultant in sampling (Theory of Sampling, TOS), chemometrics and PAT (Process Analytical Technology).

Through a 35-year academic career involving three professorships, he has conducted R&D across a wide range of application fields, primarily in process industries (mining, minerals extraction and processing, bio-fuels, recycling, environmental monitoring, nuclear waste) in environmental science a.o. In 2015 he established an international consultancy (KHE Consulting) from which he is also a dedicated contributor to IPGSA's educational outreach.

How to contribute

Sampling Science & Technology welcomes all didactic etudes, practical perspectives, illustrative case histories, as well as the occasional theoretical article aimed at the professional sampling community and all other stakeholders.

Papers in SST are published under Creative Commons licences ensuring that authors retain copyright in their work. Using the CC BY-SA license we make sure that credit must be given to the authors and adaptations must be shared under the same terms.

If you are interested in contributing to SST please contact the editor at khe.consult@gmail.com.

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